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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP14
All Species:
20.91
Human Site:
S394
Identified Species:
30.67
UniProt:
P54578
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54578
NP_001032411.1
494
56069
S394
N
T
S
D
K
K
S
S
P
Q
K
E
V
K
Y
Chimpanzee
Pan troglodytes
P60051
493
55922
S394
N
T
S
D
K
K
S
S
P
Q
K
E
V
K
Y
Rhesus Macaque
Macaca mulatta
XP_001090667
458
52239
K362
D
K
K
S
S
P
Q
K
E
V
K
Y
E
P
F
Dog
Lupus familis
XP_537306
545
61461
S445
K
T
S
D
K
K
S
S
P
Q
K
E
V
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMA1
493
55983
S393
P
N
A
N
D
K
N
S
P
P
K
E
I
K
Y
Rat
Rattus norvegicus
NP_001008302
493
55958
S393
P
N
A
N
D
K
N
S
P
P
K
E
I
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519267
431
48760
E335
K
G
S
G
T
Q
K
E
V
K
Y
E
P
F
S
Chicken
Gallus gallus
XP_419150
492
55612
G392
K
N
L
S
K
S
D
G
A
Q
K
E
V
K
Y
Frog
Xenopus laevis
Q6GNI6
523
60030
T391
C
H
S
Y
Q
E
S
T
K
Q
L
T
M
K
K
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
I403
S
A
K
L
R
R
K
I
T
T
Y
V
S
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609377
475
53689
E378
V
D
V
V
K
R
N
E
P
N
E
E
K
K
D
Honey Bee
Apis mellifera
XP_395043
497
56311
D391
K
D
R
K
D
K
I
D
S
K
K
K
V
K
Q
Nematode Worm
Caenorhab. elegans
Q17361
489
55859
K368
L
D
K
E
Q
G
D
K
I
F
D
D
G
V
A
Sea Urchin
Strong. purpuratus
XP_786966
516
58357
E405
K
S
A
A
V
T
T
E
P
K
K
D
V
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q949Y0
482
53677
K373
T
S
A
K
S
G
S
K
D
S
D
V
K
M
T
Baker's Yeast
Sacchar. cerevisiae
P43593
499
57092
T389
S
S
S
E
N
V
M
T
P
R
E
Q
Y
E
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
92.5
89.9
N.A.
96.7
96.5
N.A.
80.3
90.4
21.4
20.1
N.A.
54.6
61.7
41.9
61
Protein Similarity:
100
99.8
92.7
90.2
N.A.
98.5
98.7
N.A.
83.8
94.9
39
38.7
N.A.
71.2
80.2
61.1
76.5
P-Site Identity:
100
100
6.6
93.3
N.A.
46.6
46.6
N.A.
13.3
46.6
26.6
0
N.A.
26.6
26.6
0
33.3
P-Site Similarity:
100
100
20
93.3
N.A.
73.3
73.3
N.A.
26.6
46.6
53.3
20
N.A.
46.6
40
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.5
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.9
46.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
25
7
0
0
0
0
7
0
0
0
0
0
7
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
19
0
19
19
0
13
7
7
0
13
13
0
0
7
% D
% Glu:
0
0
0
13
0
7
0
19
7
0
13
50
7
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
13
7
% F
% Gly:
0
7
0
7
0
13
0
7
0
0
0
0
7
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
7
7
0
0
0
13
0
0
% I
% Lys:
32
7
19
13
32
38
13
19
7
19
57
7
13
63
7
% K
% Leu:
7
0
7
7
0
0
0
0
0
0
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
7
7
0
% M
% Asn:
13
19
0
13
7
0
19
0
0
7
0
0
0
0
0
% N
% Pro:
13
0
0
0
0
7
0
0
50
13
0
0
7
7
7
% P
% Gln:
0
0
0
0
13
7
7
0
0
32
0
7
0
0
7
% Q
% Arg:
0
0
7
0
7
13
0
0
0
7
0
0
0
0
0
% R
% Ser:
13
19
38
13
13
7
32
32
7
7
0
0
7
0
7
% S
% Thr:
7
19
0
0
7
7
7
13
7
7
0
7
0
0
13
% T
% Val:
7
0
7
7
7
7
0
0
7
7
0
13
38
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
13
7
7
0
44
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _